Principal Cheminformatics Scientist – Drug Discovery
Newton Colmore is working for a start-up drug discovery biotech and we are assisting them in their search for a cheminformatics expert to join their research team.
The company is seeking an experienced Cheminformatics Scientist to join their multidisciplinary team in Boston, MA and help run their cheminformatics function. As a key member of their research and development team, you will leverage your expertise in computational chemistry and data analysis to support drug discovery efforts and advance their pipeline of therapeutic candidates.
There will also be the possibility of growing a larger cheminformatics team around you, depending on the progress the company makes with their technology.
You will be Responsible for:
Develop and implement cheminformatics tools and algorithms to analyze chemical data, predict compound properties, and facilitate drug design workflows.
Collaborate with interdisciplinary teams of chemists, biologists, and computational scientists to design and optimize small molecule libraries for lead identification and optimization.
Utilize computational modelling techniques to predict molecular interactions, bioactivity profiles, and ADMET properties of drug candidates.
Maintain and enhance databases, software platforms, and data visualization tools for chemical and biological data management and analysis.
To be considered for this role you will ideally have the following;
Ideally educated to PhD-level in Computational Chemistry, Cheminformatics, Bioinformatics, or related field.
Experience in cheminformatics or computational chemistry, preferably within a start-up environment in industry.
Proficiency in programming languages such as Python, R, or Java, and experience with cheminformatics software packages (e.g., RDKit, OpenEye, ChemAxon).
Strong understanding of chemical informatics principles, molecular modeling techniques, and structure-activity relationship (SAR) analysis.
The company are open on seniority level and can tailor the role to suit the right candidate’s experience level and so do get in touch even if you feel you are either too junior or senior for the role. Newton Colmore specializes in this type of role and so we will be able to provide more opportunities to you in the future too.
The company are offering tailored packages for the right candidate that will match your expectations and experience level. This comes with a comprehensive list of benefits along with the chance to build your own team.
To find out more, make a confidential application now and Matt Lowdon, our Head of Biotechnology and Therapeutics will be in touch with more details.
Newton Colmore is a specialist medical devices and biotechnology recruitment agency, with expertise in helping our clients find the experts they need to develop ground-breaking products, therapeutics, and services.
Partnering with an expert agency in your job search is a great way to expand your horizons. As Specialist recruiters we develop our network every day, meaning they have access to roles and companies that you may not be aware of.
To complement this, we have deep insights into our markets and clients that will benefit you in the interview process, ensuring you can perform at your best. To conclude the process, we have an excellent track record of negotiating offers on behalf of our clients and candidates.
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You will gain varied laboratory-based experience working across three different departments in Product Technology & Engineering:
Product research, development and analysis
Learning the skills and techniques required to be successful in each area.
Your role, as part of a flexible team in will be to:
Generate, analyse and interpret data
Carry out problem solving, and report on your findings, contributing to Syngenta’s mission to sustainably feed the planet, while growing as a scientist and working towards your degree
Training:Scientist Level 6.
This is a flexible and inclusive programme which includes, on average, 1-day per week of online learning, with occasional onsite workshops at the University which are paid for through the programme.Training Outcome:Completion of the apprenticeship includes successful graduation with a BSc (Hons) in Applied Chemical Sciences. As part of a top 10 biotech global employer, we provide on-going development and career opportunities.Employer Description:Syngenta Crop Protection is a leader in agricultural innovation, bringing breakthrough technologies and solutions that enable farmers to grow productively and sustainably. We offer a leading portfolio of crop protection solutions for plant and soil health, as well as digital solutions that transform the decision-making capabilities of farmers. Our 17,900 employees serve to advance agriculture in more than 90 countries around the world. Syngenta Crop Protection is headquartered in Basel, Switzerland, and is part of the Syngenta Group. Our employees reflect the diversity of our customers, the markets where we operate and the communities which we serve. No matter what your position, you will have a vital role in safely feeding the world and taking care of our planet. Join us and help shape the future of agriculture. Our R&D site hosts a vibrant multi-disciplinary scientific community of around 800 people. Located between Maidenhead and Bracknell it offers a spacious and green campus environment with comprehensive sports facilities, catering facilities & social clubs. We are proud of our community and how we work together to deliver.Working Hours :36-hours per week (including 1-day per week for study), exact working days and hours TBC.Skills: Communication skills,Attention to detail,Team working,Motivated,Scientific curiosity....Read more...
Day to day duties will include, but not be limited to the following throughout training:
Learn scientific techniques and how to operate specialist equipment such as:
Thermogravimetric Analysis (TGA)
Liquid Scintillation Counting
Ultraviolet-Visible Spectrophotometry (UV-Vis)
Fourier Transform Infrared (FTIR)
Raman Spectroscopy
Particle size characterisation
Gas Chromatography Mass Spectrometry (GCMS)
Rheometry
Operate gloveboxes, to support handling radioactive and hazardous materials
Plus more:
Perform experiments using a wide range of specialist equipment
Analyse the data from experiments
Provide support to others for operation of equipment
Troubleshoot and resolve issues whilst maintaining services, and safety
Ensure equipment safety and accurancy through routine inspections, calibration, maintenance and repairs
Prepare solutions, samples, and standards for instrumental analysis and experimentation, across an exciting and wide range of areas
Provide technical support to staff and students using the nuclear laboratories as well as research and commercial activities taking place throughout the year
Keep records up to date, for using radioactive and hazardous materials in line with legislation
Record servicing details across experimental and safety equipment
Write risk assessments, COSHH (Control of Substances Hazardous to Health) assessments, and SOPs (Standard Operating Procedures) to improve processes and reduce risk
Contribute to the LEAF accreditation processes of our laboratories
Training:
In addition to your level 6 apprenticeship qualification, we offer a unique and diverse programme of training with a wide range of certified qualifications such as, Hons Degree in Chemistry, (IOSH) working safely, (COSHH), WorldSkills UK competition entry and further internal courses spanning Cryogenics, Safe Use of Laboratory Gases, Laser safety, soft skills and professional development
The initial training is deliberately broad to teach a wide range of technical competencies allowing you time to learn and grow within an everchanging Science and Engineering environment
Later in your programme you will learn to undertake key procedures, supporting research, teaching, and infrastructure surrounding a nuclear research area provision
You will spend a mixture of time working alongside our specialists to gain the technical skills required to carry out your duties as a Nuclear Scientist, whilst attending a local university to complete your degree. We will provide you with all the necessary equipment, uniform, and robust training to make this the apprenticeship of your choice
Training Outcome:
Upon completion of the apprenticeship in 5 years’ time, you will have a portfolio of key nuclear science skills and a wealth of varied, relevant experience
Most apprentices are successful in securing a role with the university or choose to continue their academic studies
Whilst we cannot guarantee a permanent position at the University of Manchester, we endeavour to match apprentices with appropriate vacancies and support them through the entire application process
Employer Description:One of the world’s leading universities built on research and teaching practices, coupled with one of the most respected apprenticeship programmes in the UK. Our programme builds its success’s year-on-year and continues to develop, matching the needs of the university and our community. We are proud of our strong reputation, supporting each of our apprentices with individualised training, specialised projects, and targeted development to build a future career at the cutting edge of technology.Working Hours :Monday - Friday, 8.30am - 4.30pm. with 1 hour for lunch.Skills: Communication skills,IT skills,Attention to detail,Organisation skills,Problem solving skills,Number skills,Analytical skills,Team working,Initiative,Passion for Science....Read more...
Senior Bioinformatics Developer – Synthetic Biology
We are searching for a senior bioinformatics developer for our biology-based tech client in Cambridge.
This is a newly created role with plenty of opportunity to grow and earn more responsibilities as the company expands. You will be developing complex bioinformatic algorithms that categorise huge amounts of data that is being produced by the company’s latest product. The company’s product is at the intersection of science and engineering which means it will be a truly multidisciplinary team of fellow scientists and engineers, all working together on this ground-breaking product.
You will be utilising your software skills to design and develop sequencing tools and algorithms which will integrate with lab systems and support tools, as well as searching for and validating open source bioinformatics tools.
You will also build an understanding of user lab processes and workflows and help develop cloud-based workflows to support the biology and chemistry research teams.
This is a great opportunity to join a company and make a real difference with your knowledge and experience, leading bioinformatics projects from day one.
We are looking for senior scientists who have developed code in Python coupled with experience in the bioinformatics field. This will be complemented by an engineering or science related degree and experience with cloud computing. Any prior knowledge of experimental NGS data would be advantageous to your application, as would hands-on knowledge of Bash.
The client is offering competitive salaries as well as a comprehensive benefits package that includes share options and a variety of other benefits.
For more information, please call Matthew Lowdon of Newton Colmore Consulting on 0044 121 268 2240 or make an application and one of our team will be in touch.
Newton Colmore Consulting is a highly specialist recruitment consultancy operating within the medical devices and biotechnology field. We help our clients find the expert engineers and scientists they need to develop and commercialise ground-breaking technologies.
Key words: Data Scientist, Machine Learning, Bioinformatics, Medical Devices, Engineering, Physics, ISO 13485, Biotechnology....Read more...
Service and upkeep materials and science equipment, glassware, consumables, and sample preparation tools.
Ensure safe working order, proper storage, and accurate cataloguing.
Perform basic maintenance on lab apparatus. Liaise with equipment manufacturers or external service engineers to troubleshoot faults and schedule contractor visits, keeping colleagues informed of progress.
Keep labs tidy, orderly, and safe on a daily basis.
Track equipment and consumable stock levels. Raise orders and coordinate with colleagues as needed.
Organise the delivery and disposal of solvents, chemicals, and materials in accordance with relevant regulations.
Monitor consumable gases used in processing and characterisation equipment.
Develop and review operating procedures and safe working practices based on daily observations and growing technical knowledge.
Under the guidance of senior technicians, demonstrate safe equipment operation, basic maintenance, and standard processes to students, staff, and visitors.
Induct users to ensure safe work in controlled or hazardous environments (e.g., clean-rooms, high-temperature labs, fume cupboards).
Identify and resolve straightforward practical issues, such as instrument errors or sample preparation issues. Escalate complex problems to senior colleagues.
Use experience and initiative to execute daily tasks and prioritise your workload with appropriate guidance. Training:To start, we offer a unique 5-year programme filled to the brim with a wide range of technical training across a multitude of skills such as chemical analysis, material science investigation and applications, research techniques, microscopy, and much more.
This training will be underpinned by in-house and external courses such as pipette, centrifuge, cryogenics, COSHH, IOSH training and the list continues. All these skills will be applied to cutting-edge equipment and technology, making this the apprenticeship to beat.
Initial training is deliberately broad to teach a wide range of technical competencies, allowing you time to learn and discover the variety of careers within an ever-changing scientific environment.
You will spend a mixture of time working alongside a day/block release course to gain the technical skills required to carry out your duties as a Materials Scientist. We will provide you with all the necessary tools and equipment, uniform, and robust training to make this the apprenticeship of your choice.Training Outcome:Upon completion of the apprenticeship in 5 years’ time, you will have a portfolio of key science and engineering skills and a wealth of varied, relevant experience.
Most apprentices are successful in securing a role with the university or choose to continue their academic studies. Opportunities to progress onto a higher apprenticeship or degree apprenticeship exist for high-performing candidates upon completion of their first apprenticeship with us.
Whilst we cannot guarantee a permanent position at the University of Manchester, we endeavour to match apprentices with appropriate vacancies and support them through the entire application process.Employer Description:One of the world’s leading universities built on research and teaching practices, coupled with one of the most respected apprenticeship programmes in the UK. Our programme builds its success’s year-on-year and continues to develop, matching the needs of the university and our community. We are proud of our strong reputation, supporting each of our apprentices with individualised training, specialised projects, and targeted development to build a future career at the cutting edge of technology.Working Hours :Monday to Friday, 9am - 5pm.(Variable times to suit workplace requirements). 1 hour for lunch.Skills: Communication skills,IT skills,Attention to detail,Organisation skills,Problem solving skills,Presentation skills,Analytical skills,Team working,Creative,Initiative,Non judgemental,Patience,Strong work ethic,Desire to progress,Passion for Science....Read more...
