ROLE OVERVIEW
A leading company in the industry is seeking a Principal Scientist / Associate Scientific Director Computational Chemistry to join their team based in the Chapel-en-le-Frith area, with a hybrid working model. Remote working from home can also be considered.
As the Principal Scientist / Associate Scientific Director, you will be instrumental in solving complex drug discovery challenges and guiding medicinal chemistry programmes.
KEY DUTIES AND RESPONSIBILITIES:
Your duties as the Principal Scientist / Associate Scientific Director will be varied however the key duties and responsibilities are as follows:
1. Deliver high-quality computational chemistry support across drug discovery programmes, from target identification through to clinical candidate nomination.
2. Apply structure-based and ligand-based small molecule drug design methods, including docking, QSAR, pharmacophore modelling, virtual screening, MD, and QM calculations, to guide medicinal chemistry and solve complex design challenges.
3. Provide expert guidance to medicinal chemists and multidisciplinary project teams, integrating computational insight with experimental data.
4. Mentor and develop computational chemists, setting high standards for scientific thinking, quality, and integrity.
ROLE REQUIREMENTS:
To be successful in your application to this exciting role as the Principal Scientist / Associate Scientific Director we are looking to identify the following on your profile and past history:
1. Relevant degree in computational chemistry or a closely related discipline.
2. Proven industry experience in drug discovery within pharma, biotech, or CRO settings, managing client projects.
3. A working knowledge and practical experience with structure-based and ligand-based small molecule drug design and the practical application of computational tools.
Key Words: Principal Scientist / Associate Scientific Director / Computational Chemistry / Drug Discovery / Medicinal Chemistry / Structure-Based Design / Ligand-Based Design / QSAR / Pharmacophore Modelling / Virtual Screening
Hyper Recruitment Solutions Ltd (HRS) is an Equal Opportunities employer. We welcome applications from anyone who meets the role requirements. HRS exclusively supports the Life Science sectors, combining recruitment expertise with scientific knowledge to help you advance your career.....Read more...
Join One of the UK’s Growing Renewable Energy Contractors Mercia Electrical Ltd is an established renewable energy contractor specialising in commercial solar PV, battery storage and EV charging installations across the UK. As our workload continues to grow, we’re looking for an experienced Plant Operator / Groundworker to join our commercial delivery team. Please note that this role is Midlands based with nationwide travel This is a varied, hands-on role combining plant operation with groundworks. We’re looking for someone who enjoys being part of the team and is happy to get involved wherever needed. About the Role Your time will be split between:
Operating telehandlers on commercial solar installations.Operating mini excavators for trenching and excavation works.Completing groundworks for commercial EV charging installations.Excavating, installing ducting and draw pits.Reinstatement of surfaces including tarmac, concrete, block paving and soft landscaping.Loading and unloading materials and supporting site logistics.Working alongside electricians and installation teams to ensure projects are completed safely and efficiently.Carrying out daily plant inspections and basic maintenance.
The role involves travelling to projects throughout the UK, with regular overnight stays during the working week where required. What We’re Looking For Essential:
CPCS or NPORS Telehandler qualification.CPCS or NPORS 360 Excavator (Mini Digger) qualification.Full UK Driving Licence.CSCS Card.Previous experience in groundworks and excavation.Experience operating plant safely on construction sites.A positive attitude and willingness to work as part of a team.Flexibility to work nationwide and stay away from home when required.
Desirable:
Experience within the renewable energy, EV charging or commercial construction sectors.First Aid at Work.Cat & Genny training.Street Works (NRSWA).Towing licence.Additional plant tickets.
What We Offer
Competitive salary of £45,000–£50,000, depending on experience.Paid overtime.Overnight allowance and accommodation when working away.Company vehicle.Pension scheme.Ongoing training and career development.Opportunities to gain additional plant and industry qualifications.Long-term career with a growing renewable energy business delivering projects across the UK.
Why Join Mercia? At Mercia Electrical Ltd, we pride ourselves on delivering high-quality renewable energy installations for commercial and industrial clients across the UK. We’re building a team of people who take pride in their work, support one another and want to be part of a company that’s growing year after year. If you’re looking for a varied role where no two weeks are the same, we’d love to hear from you. Please attach your CV to the link provided and we will be in contact. ....Read more...
Role: Care AssistantLocation: Belper (& surrounding areas)Pay: £13.00 per hourHours: Full or Part TimeShifts: Early or Late (no night shifts!)No experience required – full training and induction provided!A full UK driving licence and access to your own vehicle are essential.Join a well-established, family-run care provider with a strong reputation for delivering high-quality, person-centred care across the local community.Start a rewarding career supporting people to live independently in the comfort of their own homes.Whether you're new to care or already have experience, you'll receive full training, ongoing support and the opportunity to build a long-term career.If you're a caring and compassionate individual looking to make a real difference, we'd love to hear from you!Person specification:
Caring, compassionate and patient approachFlexible and reliable, with a positive and proactive attitudeFull driving licence and access to your own vehicleAbility to support individuals with daily living tasks, including personal care, where requiredMust have the full right to work in the UK – visa sponsorship is not available
Benefits:
Fuel allowance based on hours worked*Induction trainingFull training & development....Read more...
Are you looking for a flexible way to earn without committing to a traditional employed role?This self-employed Trade Plate Driver opportunity offers full or part time work with the flexibility to choose 3 consecutive days each week. You will work independently, drive a variety of vehicles and manage your journeys with the support of an experienced logistics team.You will need access to a driveway or suitable off-road parking space, as you may take a vehicle home in the evening to deliver to the customer the following day.Most drivers travel between vehicle collections and deliveries using trains and buses, with reasonable public transport expenses reimbursed. Others get more creative, using folding bikes or even running parts of their journey to keep fit, reduce waiting time and save money on transport.What does Trade Plate driving involve?As one of our Trade Plate Drivers, you will be provided with vehicle movements for the collection and delivery of new and used vehicles from a range of locations throughout the country, including dealerships, auction sites, compounds, hire companies, businesses and private retail customers.You will be responsible for all aspects of vehicle logistics, including:
Planning your jobs and journeysCompleting detailed and accurate vehicle appraisalsCollecting and delivering vehicles promptlyConducting professional customer handoversCompleting sign-off documentation and supporting paperwork where required
Drivers typically complete two vehicle movements per day, equating to approximately ten movements per week.An average working day is approximately 10 to 12 hours between Monday and Friday. Early starts and unpredictable finishing times are a normal part of the role.Customer service is a key part of this position, so being well-presented, polite, disciplined, organised, motivated and experienced in delivering high levels of customer service is crucial to the business.You will also need to be calm, patient, resilient and resourceful. Vehicle movements do not always go according to plan, so you must be comfortable adapting to changing circumstances and working independently.Who Could This Role Suit?The opportunity may also suit people with previous experience as a Car Rental Driver, Vehicle Service Agent, Fleet Driver, Auction Driver, Chauffeur, Professional Driver, Taxi Driver, Private Hire Driver, Courier Driver, Multi-Drop Driver, Vehicle Appraiser or Vehicle Inspector.About Intertechnic LogisticsEstablished within the industry for over 13 years, Intertechnic Logistics is a highly regarded and consistently expanding vehicle movements company.How Earnings Are Calculated
The £450–£600 weekly earning potential is based on the mileage completed.
Drivers are paid:
£20 for the first 50 miles24p per mile thereafter25p per mile after three months’ service26p per mile after six months’ service27p per mile after 12 months’ service
Actual weekly earnings will depend on the number and mileage of vehicle movements completed.To assist with your daily vehicle movements, we provide:Full insurance cover, trade plates, fuel card, tablet for completing vehicle appraisals and logging movements, professional and experienced allocators, minibus and hire-car supportIt is a requirement of our Insurance Company that all drivers hold a current Full UK Driving Licence for ten years or longer, with six or fewer active penalty points that do not include the codes TT99, DR, DD, CD or IN during the past five years.How to become a Trade Plate driver?If you feel you have the right work ethic, attitude and enthusiasm, please click apply. You will be redirected to answer a few questions and once completed will be in touch about the next stepsWe look forward to hearing from you.....Read more...
